Palladium-Catalyzed Synthesis and Isolation of Functionalized Allylboronic Acids: Selective, Direct Allylboration of Ketones**
نویسندگان
چکیده
Textbook revision: allylboronic acids, which are easily prepared from allylic alcohols, react readily and selectively with ketones without Lewis acid catalysts.
منابع مشابه
Stereocontrol in synthesis of homoallylic amines. Syn selective direct allylation of hydrazones with allylboronic acids.
Allylboronic acids directly react with acyl hydrazones, affording homoallylic amine derivatives. The reaction proceeds with very high syn selectivity, which is the opposite of the stereochemistry observed for allylboration of imines. The reaction can be carried out with both aromatic and aliphatic acyl hydrazones. Based on our studies the excellent syn stereochemistry can be explained by chelat...
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عنوان ژورنال:
دوره 51 شماره
صفحات -
تاریخ انتشار 2012